Derek Angus

  • Distinguished Professor and Mitchell P. Fink Endowed Chair, Critical Care Medicine, School of Medicine
  • Faculty in Health Policy and Management and Medicine

Research, Clinical & Academic Interests

  • Learning healthcare systems
  • Organization and delivery of critical care services
  • Sepsis, severe pneumonia and multisystem organ failure
  • Precision medicine and causal inference methods
Dr. Angus is Chair of the Department of Critical Care Medicine of both the University of Pittsburgh School of Medicine and the UPMC Healthcare System. At the University, he holds the rank of Distinguished Professor and the Mitchell P. Fink Endowed Chair in Critical Care Medicine with secondary appointments in Medicine, Health Policy and Management, and Clinical and Translational Science and he directs the CRISMA (Clinical Research, Investigation, and Systems Modeling of Acute Illnesses) Center. He also co-directs the UPMC ICU Service Center, responsible for the provision of ICU services across the 20-plus hospital system. Upon completing his undergraduate studies at the University of Glasgow School of Medicine, Glasgow, United Kingdom, Dr. Angus completed his intern and residency training at the Western Infirmary and the Southern General Hospital in Glasgow. He then traveled to the U.S. and obtained his MPH from the University of Pittsburgh Graduate School of Public Health. During this time he was a Fellow of Critical Care Medicine, a Research Fellow, and a Research Fellow in Disaster and Emergency Medicine at the University of Pittsburgh. Dr. Angus’ research interests include clinical, epidemiologic, and translational studies of sepsis, pneumonia, and multisystem organ failure and health services research of the organization and delivery of critical care services. Dr. Angus has led several large NIH-funded multicenter studies in the critically ill, the most recent of which is ProCESS (Protocolized Care for Early Septic Shock), a 40-center study focusing on how to best provide early resuscitation for septic shock. Dr. Angus has published several hundred papers, reviews and book chapters, and is currently section editor for “Caring for the Critically Ill” for JAMA. He is the recipient of numerous awards, including the Presidential Citation Award of the Society of Critical Care Medicine (1999, 2004-2006, 2008, 2011, 2013), the Master of Critical Care Medicine from the American College of Critical Care Medicine (2012), Best Doctors of America (2005-present), and the Best Doctors in Pittsburgh (2012-present), Top 10 Outstanding Clinical Research Achievements from the Clinical Research Forum (2015), and an Honorary Member of the European Society of Intensive Care Medicine (2015). Dr. Angus is a member of the Society of Critical Care Medicine, the American College of Chest Physicians, the American Thoracic Society, the Association for Health Services Research, the European Society of Intensive Care Medicine, and the American College of Critical Care Medicine. View a list of Dr. Angus’ publications here.

MB, ChB, University of Glasgow School of Medicine, 1984
MRCP (UK), Internal Medicine, University of Glasgow teaching hospitals, 1988
MPH, Graduate School of Public Health, University of Pittsburgh, 1992
Fellowship, Critical Care Medicine, University of Pittsburgh School of Medicine, 1991
Fellowship, Safar International Resuscitation Research Center, University of Pittsburgh, 1992

Selected Publications

Angus DC, Kelley MA, Schmitz RJ, White A, Popovich J. Current and projected workforce requirements for care of the critically ill and patients with pulmonary disease. JAMA 2000;284(21):2762-70.

Angus DC, van der Poll T. Severe Sepsis and Septic Shock. N Engl J Med 2013; 369(21):2062-2063.

The ProCESS Investigators, Yealy DM, Kellum JA, Huang DT, Barnato AE, Weissfeld LA, Pike F, Terndrup T, Wang HE, Hou PC, LoVecchio F, Filbin MR, Shapiro NI, Angus DC. A randomized trial of protocol-based care for early septic shock. N Engl J Med 2014; 370(18):1683-93.

Angus DC. Fusing Randomized Trials with Big Data; the Key to Self-learning Health Care Systems? JAMA 2015; 314(8):767-768.

Full listing on Pub Med