Donald S Burke

MD
  • Distinguished University Professor of Health Science and Policy, Epidemiology
  • Jonas Salk Chair in Population Health
  • Member, Public Health Dynamics Lab
  • Dean Emeritus, Graduate School of Public Health
Education
  • Bachelor of Arts Degree, Western Reserve University, Cleveland, Ohio, 1967 (chemistry major; honors in biology; magna cum laude; Phi Beta Kappa)
  • Doctorate in Medicine, Harvard Medical School, Boston, Massachusetts, 1971
  • Clinical Fellow in Medicine (Intern & Junior Resident Physician), Harvard University and the Boston City Hospital, Boston, Massachusetts, 1971-73
  • Clinical Fellow in Medicine (Senior Resident Physician), Harvard University and the Massachusetts General Hospital, Boston, Massachusetts, 1975-76
  • Research Fellow in Infectious Diseases, Walter Reed Army Medical Center, Washington, DC, 1976-78
Selected Publications
  • Castanha PMS, Tuttle DJ, Kitsios GD, Jacobs JL, Braga-Neto U, Duespohl M, Rathod S, Marti MM, Wheeler S, Naqvi A, Staines B, Mellors J, Morris A, McVerry BJ, Shah F, Schaefer C, Macatangay BJC, Methe B, Fernandez CA, Barratt-Boyes SM,Burke D, Marques ETA. IgG response to SARS-CoV-2 and seasonal coronaviruses contributes to complement overactivation in severe COVID-19 patients.J Infect Dis. 2022 Mar 10:jiac091. doi: 10.1093/infdis/jiac091.
  • Burke DS, Jalal H. Reply commentary by Jalal and Burke.Int J Drug Policy. 2022; 104:103674.doi: 10.1016/j.drugpo.2022.103674
  • Jalal H, Burke DS. Exponential growth of drug overdose poisoning and opportunities for intervention. Addiction. 2022;117(5):1200-1202. doi:10.1111/add.15841
  • Lee K, Jalal H, Raviotta JM, Krauland MG, Zimmerman RK, Burke DS, Roberts MS. Estimating the Impact of Low Influenza Activity in 2020 on Population Immunity and Future Influenza Seasons in the United States. Open Forum Infect Dis. 2021;9(1):ofab607. doi: 10.1093/ofid/ofab607Yu
  • J, Collins ND, Mercado NB, McMahan K, Chandrashekar A, Liu J, Anioke T, Chang A, Giffin VM, Hope DL, Sellers D, Nampanya F, Gardner S, Barrett J, Wan H, Velasco J, Teow E, Cook A, Van Ry A, Pessaint L, Andersen H, Lewis MG, Hofer C, Burke DS, Barkei EK, King HAD, Subra C, Bolton D, Modjarrad K, Michael NL, Barouch DH. Protective Efficacy of Gastrointestinal SARS-CoV-2 Delivery against Intranasal and Intratracheal SARS-CoV-2 Challenge in Rhesus Macaques.J Virol. 2022; 96(2): e0159921. doi: 10.1128/JVI.01599-21.
  • Jalal H, Burke DS. Carfentanil and the rise and fall of overdose deaths in the United States. Addiction. 2021;116(6):1593-1599. doi: 10.1111/add.15260. Huang AT, Garcia-Carreras B, Hitchings MDT, Yang B, Katzelnick LC, Rattigan SM, Borgert BA, Moreno CA, Solomon BD, Trimmer-Smith L, Etienne V, Rodriguez-Barraquer I, Lessler J, Salje H, Burke DS, Wesolowski A, Cummings DAT. A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity. Nat Commun. 2020 ;11(1):4704. doi: 10.1038/s41467-020-18450-4.
  • Burke DS, Halstead S, Monath TP. Major General (Ret) Philip King Russell.Am J Trop Med Hyg. 2021;104(5):1946–7. doi: 10.4269/ajtmh.21-1932
  • Jalal H, and Burke DS. Hexamaps for Age-Period-Cohort Data Visualization in R. Epidemiology. 2020 Nov 1; 31(6): e47–49. doi: 10.1097/EDE.0000000000001236
  • Sinclair, David R.; Grefenstette, John J.; Krauland, Mary G.; Galloway, David D.; Frankeny, Robert J.; Travis, Clayton; Burke, Donald S.; Albert, Steven M.; and Roberts, Mark S. (2019) "Interventions in measles outbreaks: the potential reduction in cases associated with school suspension and vaccination interventions,"J ournal of Applied Research on Children: Informing Policy for Children at Risk: Vol.10:Iss.2, Article10.
  • Sinclair DR, Grefenstette JJ, Krauland MG, Galloway DD, Frankeny RJ, Travis C, Burke DS, Roberts MS. Forecasted size of measles outbreaks associated with vaccination exemptions for schoolchildren. JAMA Netw Open. 2019 Aug 2;2(8):e199768. doi: 10.1001/jamanetworkopen.2019.9768.
  • van Panhuis WG, Cross A, Burke DS. Project Tycho 2.0: A repository to improve the integration and reuse of data for global population health. J Am Med Inform Assoc. 2018 2018;25(12):1608-1617. doi:10.1093/jamia/ocy123.
  • Jalal H, Buchanich JM, Roberts MS, Balmert LC, Zhang K, Burke DS. Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016.Science. 2018;361(6408). pii: eaau1184. doi: 10.1126/science.aau1184.
  • Espana G, Grefenstette J, Perkins A, Torres C, Campo Carey A, Diaz H, de la Hoz F,Burke DS, van Panhuis WG. Exploring scenarios of chikungunya mitigation with a data-driven agent-based model of the 2014-2016 outbreak in Colombia.Sci Rep. 2018;8(1):12201. doi:10.1038/x41598-018-30647-8.
  • Buchanich JM, Balmert LC, Williams KE, Burke DS. The effect of incomplete death certificates on estimates of unintentional opioid-related overdose deaths in the United States, 1999-2015.Public Health Rep. 2018;133(4):423-431. doi: 10.1177/0033354918774330.
  • Buchanich JM, Doerfler SM, Lann MF, Marsh GM,Burke DS. Improvement in racial disparities in years of life lost in the USA since 1990.PLoS One. 2018 Apr25;13(4):e0194308. doi:10.1371/journal.pone.0194308.
  • Nascimento EJM, Huleatt JW, Cordeiro MT, Castanha PMS, George JK, Grebe E, Welte A, Brown M, Burke DS, Marques ETA. Development of antibody biomarkers of long term and recent dengue virus infections. J Virol Methods, 2018 Jul;257:62-68. doi:10.1016/j.jviromet.2018.04.009.
  • Marques ETA, Burke DS. Tradition and innovation in development of a Zika vaccine. Lancet, 2018 Feb 10:391(10120):516-517. doi:10.1016/S0140-6736(17)33107-0.
  • Farrow DC, Brooks LC, Hyun S, Tibshirani RJ, Burke DS, Rosenfeld R. A human judgment approach to epidemiological forecasting. PLoS Comput Bio, 2017 Mar 10;13(3):e1005248. doi:10.1371/journal.pci.1005248.
  • Burke DS. Forecasting the opioid epidemic. Science. 2016 Nov 4;354(6312):529. doi:10.1126/science.aa12943.
  • Zimmerman RK, Nowalk MP, Chung J, Jackson ML, Jackson LA, Petrie JG, Monto AS, McLean HQ, Belongia EA, Gaglani M, Murthy K, Fry AM, Flannery B; U.S. Flu VE Investigators. 2014-2015 Influenza Vaccine Effectiveness in the United States by vaccine type. Clin Infect Dis. 2016 Dec 15;63(12):1564-1573. doi:10.1093/cid/ciw635.
  • Gearhart TL, Montelaro RC, Schurdak ME, Pilcher CD, Rinaldo CR, Kodadek T, Park Y, Islam K, Yurko R, Marques ET Jr, Burke DS. Selection of a potential diagnostic biomarker for HIV infection from a random library of non-biological synthetic peptoid oligomers.J Immunol Methods. 2016 Aug;435:85-89. doi:10.1016/j.jim.2016.05.001.
  • Buchanich JM, Balmert LC, Pringle JL, Williams KE, Burke DS, Marsh GM,. Patterns and trends in accidental poisoning death rates in the US, 1979-2014.Preventive Medicine. 2016 Apr 13. doi:10.1016/j.ypmed.2016.04.007.
  • Metcalf CJE, Farrar J, Cutts F, Basta N, Graham AL, Lessler J, Ferguson N, Burke D, Grenfell BT. Use of Serological surveys to generate key insights of the changing global landscape of infectious disease.Lancet. 2016 Aug 13:388(10045):728-30. doi:10.1016/S0140-6736(16)30164-7.
  • Balmert LC, Buchanich JM, Pringle JL, Williams KE, Burke DS, Marsh GM. Patterns and Trends in Accidental Poisoning Deaths: Pennsylvania's Experience 1979-2014.PLoS One. 2016;11(3):e0151655. doi:10.1371/journal.pone.0151655.
  • Dalziel BD, Bjørnstad ON, van Panhuis WG, Burke DS, Metcalf CJ, Grenfell BT. Persistent Chaos of Measles Epidemics in the Prevaccination United States Caused by a Small Change in Seasonal Transmission Patterns. PLoS Computational Biology. 2016 Feb;12(2):e1004655. doi:10.1371/journal.pcbi.1004655.
  • van Panhuis WG, Choisy M, Xiong X, Chok NS, Akarasewi P, Iamsirithaworn S, Lam SK, Chong CK, Lam FC, Phommasak B, Vongphrachanh P, Bouaphanh K, Rekol H, Hien NT, Thai PQ, Duong TN, Chuang JH, Liu YL, Ng LC, Shi Y, Tayag EA, Roque VG Jr, Lee Suy LL, Jarman RG, Gibbons RV, Velasco JM, Yoon IK, Burke DS, Cummings DA. Region-wide synchrony and traveling waves of dengue across eight countries in Southeast Asia.Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13069-74. doi: 10.1073/pnas.1501375112.
  • Rodriguez-Barraquer I, Mier-y-Teran-Romero L, Ferguson N, Burke DS, Cummings DA.&nbsp Differential efficacy of dengue vaccine by immune status.&nbsp Lancet. 2015 May 2;385(9979):1726. doi: 10.1016/S0140-6736(15)60889-3.
  • Farrow DC, Burke DS, Rosenfeld R. Computational Characterization of Transient Strain-Transcending Immunity against Influenza A.&nbsp PLoS One. 2015 May 1;10(5):e0125047. doi: 10.1371/journal.pone.0125047. eCollection 2015.
  • Ruberto I, Marques E, Burke DS, Van Panhuis WG. The availability and consistency of dengue surveillance data provided online by the World Health Organization. PLoS Negl Trop Dis. 2015 Apr 14;9(4):e0003511. doi: 10.1371/journal.pntd.0003511. eCollection 2015 Apr.
  • van Panhuis WG, Paul P, Emerson C, Grefenstette J, Wilder R, Herbst AJ, Heymann D, Burke DS.&nbsp A systematic review of barriers to data sharing in public health.&nbsp BMC Public Health. 2014 Nov 5;14:1144. doi: 10.1186/1471-2458-14-1144.
  • Lukens S, DePasse J, Rosenfeld R, Ghedin E, Mochan E, Brown ST, Grefenstette J, Burke DS, Swigon D, Clermont G.&nbsp A large-scale immuno-epidemiological simulation of influenza A epidemics. BMC Public Health. 2014 Sep 29;14:1019. doi: 10.1186/1471-2458-14-1019.
  • LeBreton M, Switzer WM, Djoko CF, Gillis A, Jia H, Sturgeon MM, Shankar A, Zheng H, Nkeunen G, Tamoufe U, Nana A, Le Doux Diffo J, Tafon B, Kiyang J, Schneider BS, Burke DS, Wolfe ND. A gorilla reservoir for human T-lymphotropic virus type 4.&nbsp Emerg Microbes Infect. 2014 Jan;3(1):e7. doi: 10.1038/emi.2014.7.
  • van Panhuis WG, Grefenstette J, Jung SY, Chok NS, Cross A, Eng H, Lee BY, Zadorozhny V, Brown S, Cummings D, Burke DS. Contagious diseases in the United States from 1888 to the present.  N Engl J Med. 2013 Nov 28;369(22):2152-8. doi: 10.1056/NEJMms1215400.
  • Rodriguez-Barraquer I, Mier-y-Teran-Romero L, Schwartz IB, Burke DS, Cummings DA.&nbsp Potential opportunities and perils of imperfect dengue vaccines.Vaccine. 2014 Jan 16;32(4):514-20. doi: 10.1016/j.vaccine.2013.11.020.
  • Azman AS, Stark JH, Althouse BM, Vukotich CJ Jr, Stebbins S, Burke DS, Cummings DA.&nbsp Household transmission of influenza A and B in a school-based study of non-pharmaceutical interventions. Epidemics. 2013 Dec;5(4):181-6. doi: 10.1016/j.epidem.2013.09.001.
  • Yonas MA, Burke JG, Brown ST, Borrebach JD, Garland R, Burke DS, Grefenstette JJ. Dynamic simulation of crime perpetration and reporting to examine community intervention strategies. Health Educ Behav. 2013 Oct;40(1 Suppl):87S-97S. doi: 10.1177/1090198113493090.
  • Rodriguez-Barraquer I, Mier-y-Teran-Romero L, Burke DS, Cummings DA. Challenges in the interpretation of dengue vaccine trial results. PLoS Negl Trop Dis. 2013 Aug 29;7(8):e2126. doi: 10.1371/journal.pntd.0002126. eCollection 2013.
  • Gibbons RV, Nisalak A, Yoon IK, Tannitisupawong D, Rungsimunpaiboon K, Vaughn DW, Endy TP, Innis BL, Burke DS, Mammen MP Jr, Scott RM, Thomas SJ, Hoke CH Jr. A model international partnership for community-based research on vaccine-preventable diseases: the Kamphaeng Phet-AFRIMS Virology Research Unit (KAVRU). Vaccine. 2013&nbsp 23;31(41):4487-500. doi: 10.1016/j.vaccine.2013.07.082. Review.
  • Burke DS, Grefenstette JJ. Toward an integrated meta-model of public health dynamics for preparedness decision support. Public Health Manag Pract. 2013 Sep-Oct;19 Suppl 2:S12-5. doi: 10.1097/PHH.0b013e31828a842f.
  • Reich NG, Shrestha S, King AA, Rohani P, Lessler J, Kalayanarooj S, Yoon IK, Gibbons RV, Burke DS, Cummings DA. Interactions between serotypes of dengue highlight epidemiological impact of cross-immunity. J R Soc Interface. 2013;10(86):20130414. doi: 10.1098/rsif.2013.0414.
  • Kumar S, Grefenstette JJ, Galloway D, Albert SM, Burke DS.&nbsp Policies to reduce influenza in the workplace: impact assessments using an agent-based model. Am J Public Health. 2013 Aug;103(8):1406-11. doi: 10.2105/AJPH.2013.301269.
  • Toner ES, Adalja AA, Nuzzo JB, Inglesby TV, Henderson DA, Burke DS. Assessment of serosurveys for H5N1. Clin Infect Dis. 2013 May;56(9):1206-12. doi: 10.1093/cid/cit047.
  • Ma D, Jasinska A, Kristoff J, Grobler JP, Turner T, Jung Y, Schmitt C, Raehtz K, Feyertag F, Martinez Sosa N, Wijewardana V, Burke DS, Robertson DL, Tracy R, Pandrea I, Freimer N, Apetrei C; International Vervet Research Consortium. SIVagm infection in wild African green monkeys from South Africa: epidemiology, natural history, and evolutionary considerations. PLoS Pathog. 2013 Jan;9(1):e1003011. doi: 10.1371/journal.ppat.1003011.
Department/Affiliation