Cai publishes in Communications Biology

PhD student Manqi Cai’s article “scMD facilitates cell type deconvolution using single-cell DNA methylation references”  was published in the Communications Biology Journal. Their research introduces scMD (single cell Methylation Deconvolution), a groundbreaking framework for extracting cell-type-specific information from bulk DNA methylation data, especially in complex tissues like the brain. This method surpasses current techniques and accurately identifies cell types associated with Alzheimer's disease. Cai is advised by Jiebiao Wang and Chris McKennan (Pitt Statistics).